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Replicate Nutanix Cluster to vSAN Cluster site-to-site

  • December 28, 2025
  • 1 reply
  • 15 views
H

Hi everyone,

A customer currently operates a VMware vSAN cluster at their primary site and is planning to deploy a new HCI platform at a secondary site. One of the key requirements is that the new HCI cluster must be able to replicate workloads to the existing VMware vSAN environment.

My question is the following:

  • Is it feasible to propose Nutanix with AHV for the secondary site while keeping VMware vSAN at the primary site?

  • If yes, which third-party solution would be recommended to ensure reliable replication between Nutanix AHV and VMware vSAN?

  • If not, what alternative HCI architecture would you recommend to meet this requirement?

Thanks in advance for your insights and feedback.

1 reply

J
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  • jamali.ahmad
  • Outrider
  • December 29, 2025

Hi,

Nutanix has the concept of Cross-Hypervisor DR, but that works at prism data protection workflow,meaning you need to have different hypervisor on top of Nutanix environment.
so your source and destination should be on top of Nutanix environment .

 

and it has below limitation:

  • Doesn't preserve SCSI controllers (Nutanix uses LSI logic on failback)

  • No support for UEFI boot

  • Doesn't preserve vSphere High Availability (HA) and Distributed Resource Scheduler (DRS) settings

  • No support for hypervisor-based snapshots, VMware VSS, or linked clones

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