Deploying a Nutanix cluster running Nutanix AHV and AOS on Cisco UCS hardware with Fabric Interconnects (FIs) provides a resilient, high-performance hyperconverged infrastructure. Combining Nutanix with UCS Fabric Interconnects requires proper VLAN configurations, network mapping, and a seamless Foundation process.
Furthermore, managing multi-cluster environments or advanced management services often requires deploying Prism Central. In this guide, we will walk through the end-to-end architecture: deploying a 3-node Nutanix AHV/AOS cluster, followed by deploying Prism Central as a VM on an ESXi host, registering Prism Element to it, and configuring network settings via the GUI.
Architecture Overview & Prerequisites
Architecture Topology
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Cluster Nodes: 3 x Cisco UCS C-Series Rack Servers (or UCS B-Series Blades)
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Control Plane: 2 x Cisco UCS Fabric Interconnects (FI 6400 / 6300 Series) in High Availability mode (FI-A and FI-B)
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Storage & Hypervisor: Nutanix AOS & Nutanix AHV
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Management Engine: Prism Central deployed as a standalone Virtual Machine on an external/existing VMware ESXi host.
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Fabric Connections: Dual-homed connectivity (each node has redundant uplinks split between FI-A and FI-B).
+-------------------------------------------------------+
| Core Switches / Upstream |
+---------------------------+---------------------------+
|
+-----------+-----------+
| |
+-------+-------+ +-------+-------+
| Cisco UCS FI-A| | Cisco UCS FI-B|
+-------+-------+ +-------+-------+
| |
+-----------+-----------+-----------+-----------+
| | |
+------+--------+ +------+--------+ +------+--------+
| Nutanix Node 1| | Nutanix Node 2| | Nutanix Node 3|
+---------------+ +---------------+ +---------------+
Pre-requisites Checklist
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UCS Manager / Intersight: Fully configured Fabric Interconnect pair with active uplinks to upstream switches.
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IP Address Allocation:
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Out-of-band IPMI / Cisco IMC IPs for each node.
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Host IPs (AHV Hypervisor) for 3 nodes.
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Controller VM (CVM) IPs for 3 nodes.
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Cluster Virtual IP (VIP) for Nutanix Prism Element.
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Prism Central VM IP (for deployment on ESXi).
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Nutanix Foundation VM / Deployment Laptop IP.
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VLANs Configured on UCS FI:
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Management VLAN (for AHV, CVM, and IPMI/CIMC).
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Data / Storage VLANs.
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VM Guest Networks.
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Step 1: Cisco UCS Fabric Interconnect Configuration
Before starting the Foundation process, the UCS network profiles must be correctly provisioned:
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Create MAC Address Pools: Define redundant MAC pools for vNICs across FI-A and FI-B.
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Configure VLANs:
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In UCSM / Intersight, navigate to LAN -> VLANs and create your required Nutanix Management and Production VLANs.
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Mark the Nutanix Management VLAN as Native if untagged traffic is used during initial deployment.
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Configure Service Profiles / VNIC Templates:
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Assign two physical vNICs per server: vNIC_A (bound to FI-A) and vNIC_B (bound to FI-B).
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Set MTU to 9000 (Jumbo Frames) on UCS QOS policies for optimal AOS storage performance.
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Step 2: Preparing Nutanix Foundation & Environment Setup
To ensure uninterrupted communication (IPv6 discovery, SSH, TFTP, and imaging protocols) during the Foundation process, proper firewall management is essential:
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Disable Host Laptop Firewall: Completely turn off the local firewall (Windows Firewall or macOS Firewall) on your management laptop to allow unhindered traffic between your machine, the Foundation VM, and the target nodes.
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Disable Foundation VM Firewall: Ensure the internal OS firewall inside the Nutanix Foundation VM is stopped:
Bashsudo systemctl stop firewalld
sudo systemctl disable firewalld -
Connect your deployment laptop/VM to the same flat L2 broadcast domain as the CIMC/IPMI ports of the 3 Cisco nodes.
Step 3: Cluster Discovery, Imaging & Prism Element Initialization
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Launch Discovery: Open Nutanix Foundation and run a scan to discover the 3 Cisco UCS nodes via IPv6 / MAC address.
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Select Software Stack: Select Nutanix AOS and Nutanix AHV as the target deployment stack.
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Network & Node Configuration:
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Assign static IPs for CIMC, AHV Host, and CVM for all 3 nodes.
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Provide Subnet Mask, Gateway, and Management VLAN ID.
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Create Cluster: Check "Create Cluster", set the Cluster Name, Redundancy Factor (RF2), Cluster Virtual IP (VIP), and DNS/NTP servers.
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Start Foundation Process: Click Start Foundation. Once finished, the 3-node AHV/AOS cluster will be running.
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Access Prism Element: Open
https://<Cluster-Virtual-IP>:9440, set a new admin password, and accept the EULA.
Step 4: Deploying Prism Central on ESXi & Registering Prism Element
Once Prism Element is up and running, proceed with deploying Prism Central as a VM on an external VMware ESXi host:
1. Prism Central VM Deployment (OVA on ESXi)
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Download the Prism Central OVA package for ESXi from the Nutanix Portal.
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Log in to your VMware ESXi / vCenter server.
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Deploy the OVF/OVA template, allocating the required CPU, RAM, and Storage resources (Small/Medium size based on environment requirements).
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Power on the Prism Central VM and complete initial IP/Network setup via console or Web UI wizard.
2. GUI Network & Cluster Configuration in Prism Central
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Access Prism Central GUI at
https://<Prism-Central-IP>:9440. -
Log in with default credentials (
admin), set a new password, and navigate to Prism Central Settings. -
Network Configuration (GUI):
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Configure Virtual Switches / Subnets under Network Settings.
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Assign static management IP, subnet mask, gateway, and DNS/NTP servers directly through the GUI interface.
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3. Registering Prism Element to Prism Central
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Open Prism Element (
https://<Cluster-Virtual-IP>:9440). -
Navigate to Gear Icon (Settings) -> Prism Central Registration.
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Click Register, enter the Prism Central IP Address and admin credentials.
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Confirm registration. Once complete, your 3-node Nutanix AHV cluster is fully integrated and managed via Prism Central!
