Best answer by jh
Justin from Nutanix here. We do support running the vSphere Distributed Virtual Switch. There's a document on our Support Portal (portal.nutanix.com) that details the procedure we recommend. If you're signed in, this link will get you there (https://na4.salesforce.com/articles/Knowledge_Base/Configuring-VMware-Distributed-Switch-vDS-on-Nutanix-Platform)
If not, log in to the Portal, and under Documentation, go to Knowledge Base, then search for "Distributed Switch".
Hope that helps.