According to the documentation, Backplane traffic segmentation is not supported in a configuration for "ESXi clusters in which the CVM is connected to a VMware distributed virtual switch" .
What I'd like to understand is whether this is related to technical reasons, or it is just a configuration limitation of the CVM installer/Prism management?
So far I counldn't find a comprehensive guide/document about setting up a Nutanix cluster with vSphere distributed switches, and nodes with 2x10gbps each. It doesn't seem to make sense to me to set this up with standard swtches (i.e. no Network I/O control) where all traffic (VM, storage, vMotion, ...) use the same physical uplinks.