If you have 5 blocks with 8 nodes installed in the same rack, will you keep using RF = 2 or 3, or will you use fault tolerance domain to block instead?
Policies like Redundancy factor and Fault tolerance are often best implemented based on the setup, requirement and use-case of the environment and on a case by case basis.
I would like to suggest you to go through this document: https://portal.nutanix.com/page/documents/details?targetId=Web-Console-Guide-Prism-v5_17:arc-failure-modes-c.html and decide which would suit better for your setup.
You can focus on the Block awareness section of this document: https://portal.nutanix.com/page/documents/details?targetId=Web-Console-Guide-Prism-v5_17:arc-block-awareness-c.html and evaluate if it would be a good idea to move the fault tolerance domain to Block type.
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